transmembrane serine protease 7 (TMPRSS7)

Structure: - belongs to the peptidase S1 family - contains 2 CUB domains - contains 2 LDL-receptor class A domains - contains 1 peptidase S1 domain

General

glycoprotein transmembrane serine protease

Properties

SIZE: MW = 64 kD entity length = 572 aa COMPARTMENT: cellular membrane MOTIF: signal sequence {1-25} CUB domain {26-89} MOTIF: cysteine residue {C28} MODIFICATION: cysteine residue {C51} cysteine residue {C51} MODIFICATION: cysteine residue {C28} CUB domain {94-210} MOTIF: cysteine residue {C94} MODIFICATION: cysteine residue {C125} cysteine residue {C125} MODIFICATION: cysteine residue {C94} N-glycosylation site {N144} N-glycosylation site {N208} LDL-receptor class A {212-248} MOTIF: cysteine residue {C213} MODIFICATION: cysteine residue {C225} cysteine residue {C220} MODIFICATION: cysteine residue {C238} cysteine residue {C225} MODIFICATION: cysteine residue {C213} cysteine residue {C232} MODIFICATION: cysteine residue {C247} cysteine residue {C238} MODIFICATION: cysteine residue {C220} cysteine residue {C247} MODIFICATION: cysteine residue {C232} N-glycosylation site {N255} N-glycosylation site {N281} LDL-receptor class A {287-324} MOTIF: cysteine residue {C288} MODIFICATION: cysteine residue {C300} N-glycosylation site {N290} cysteine residue {C295} MODIFICATION: cysteine residue {C314} cysteine residue {C300} MODIFICATION: cysteine residue {C288} cysteine residue {C308} MODIFICATION: cysteine residue {C323} cysteine residue {C314} MODIFICATION: cysteine residue {C295} cysteine residue {C323} MODIFICATION: cysteine residue {C308} S1 domain {335-569} MOTIF: cysteine residue {C360} MODIFICATION: cysteine residue {C376} histidine residue {H375} cysteine residue {C376} MODIFICATION: cysteine residue {C360} aspartate residue {D423} cysteine residue {C459} MODIFICATION: cysteine residue {C525} cysteine residue {C491} MODIFICATION: cysteine residue {C504} cysteine residue {C504} MODIFICATION: cysteine residue {C491} cysteine residue {C515} MODIFICATION: cysteine residue {C545} serine residue {S519} cysteine residue {C525} MODIFICATION: cysteine residue {C459} cysteine residue {C545} MODIFICATION: cysteine residue {C515}

Database Correlations

UniProt Q7RTY8 PFAM correlations

References

UniProt :accession Q7RTY8