Transmembrane protein 176B (protein LR8, TMEM176B, LR8)

Function: - role in process of maturation of dendritic cells - required for development of cerebellar granule cells Structure: belongs to the TMEM176 family Compartment: - nuclear envelope Expression: - expressed in lung & dermal fibroblasts - down-regulated in activated dendritic cells Pathoology: up-regulated in fibrotic lung

General

nuclear protein transmembrane 4 protein

Properties

COMPARTMENT: cellular membrane MOTIF: cytoplasmic domain {N-TERMINAL} transmembrane domain {TM1} exoplasmic loop LOOP#: 1 transmembrane domain {TM2} cytoplasmic loop transmembrane domain {TM3} exoplasmic loop LOOP#: 2 transmembrane domain {TM4} cytoplasmic domain {C-TERMINAL}

Database Correlations

UniProt Q3YBM2 Pfam PF06077

References

UniProt :accession Q3YBM2