tetraspanin-4; Tspan-4; novel antigen 2; NAG-2; transmembrane 4 superfamily member 7 (TSPAN4, NAG2, TM4SF7)

Function: - forms a complex with integrins Structure: belongs to the tetraspanin (TM4SF) family Compartment: membrane Expression: - expressed in multiple tissues - not expressed in brain, lymphoid cells, & platelets

General

glycoprotein tetraspanin (transmembrane-4-superprotein)

Properties

SIZE: entity length = 238 aa MW = 26 kD COMPARTMENT: cellular membrane MOTIF: cytoplasmic domain {1-13} transmembrane domain {14-34} exoplasmic loop {35-55} transmembrane domain {56-76} cytoplasmic loop {77-85} transmembrane domain {86-106} exoplasmic loop {107-201} MOTIF: N-glycosylation site {N152} N-glycosylation site {N161} transmembrane domain {202-222} cytoplasmic domain {223-238}

Database Correlations

OMIM 602644 UniProt O14817 Pfam PF00335 Entrez Gene 7106 Kegg hsa:7106

References

UniProt :accession O14817