transmembrane 4 protein

N- & C-terminal domains are characteristically cytoplasmic.

Specific

1-acyl-sn-glycerol-3-phosphate acyltransferase delta; 1-acylglycerol-3-phosphate O-acyltransferase 4; 1-AGP acyltransferase 4; 1-AGPAT 4; lysophosphatidic acid acyltransferase delta; LPAAT-delta (AGPAT4) 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase; cholestenol delta-isomerase; delta(8)-delta(7) sterol isomerase; D8-D7 sterol isomerase; emopamil-binding protein (EBP) ALS 2 chromosomal region candidate gene protein 4; transmembrane protein 237 (ALS2CR4 TMEM237) ARL-6-interacting protein 1; ADP-ribosylation-like factor 6-interacting protein 1; Aip-1 (ARL6IP, ARL6IP1, KIAA0069) bestrophin bifunctional apoptosis regulator; RING finger protein 47 (BFAR, BAR, RNF47) BRI3-binding protein (I3-binding protein, cervical cancer 1 proto-oncogene-binding protein KG19, HCCR-1, BRI3BP, KG19) Ca+2 release-activated Ca+2 channel protein 1 (transmembrane protein 142A, protein orai-1, TMEM142A, CRACM1, ORAI1) clarin-2 (CLRN2) claudin claudin domain-containing protein 2 (CLDND2) claudin-24 (CLDN24) claudin-34 (CLDN34) connexin (gap-junction protein) cytochrome p450 5A; thromboxane A [TxA] synthase 1 (TBXAS1, CYP5, CYP5A1) derlin (degradation in endoplasmic reticulum protein, Der1-like protein, DERtrin) dolichyldiphosphatase 1; dolichyl pyrophosphate phosphatase 1 (DOLPP1) E3 ubiquitin-protein ligase MARCH5 (membrane-associated RING finger protein 5, membrane-associated RING-CH protein V, MARCH-5, RING finger protein 153, MARCH5, RNF153) epithelial membrane protein ergosterol biosynthetic protein 28 (C14orf1) fatty acid desaturase 2 (delta(6) fatty acid desaturase, delta(6) desaturase, D6D, FADS2) fatty acid desaturase 2-like protein (FADS2P1) fatty acid desaturase 3 (cytochrome b5-related protein, FADS3, CYB5RP) glycine receptor subunit beta; glycine receptor 58 kD subunit (GLRB) Golgi apparatus membrane protein TVP23 homolog A (TVP23A, FAM18A) Golgi apparatus membrane protein TVP23 homolog B (TVP23B, FAM18B, FAM18B1, CGI-148, NPD008) high affinity immunoglobulin epsilon receptor subunit beta; FcERI; IgE Fc receptor subunit beta; Fc epsilon receptor I beta-chain; membrane-spanning 4-domains subfamily A member 2 (MS4A2, APY, FCER1B, IGER) K+ channel subfamily K member 10; outward rectifying K+ channel protein TREK-2; TREK-2 K+ channel subunit (KCNK10, TREK2) K+ channel subfamily K member 12 (tandem pore domain halothane inhibited potassium channel 2, THIK-2, KCNK12) K+ channel subfamily K member 15; acid-sensitive K+ channel protein TASK-5; TWIK-related acid-sensitive K+ channel 5; Two pore K+ channel KT3.3 (KCNK15, TASK5) K+ channel subfamily K member 16; TWIK-related alkaline pH-activated K+ channel 1; 2P domain K+ channel Talk-1 (KCNK16 TALK1) K+ channel subfamily K member 17; TWIK-related alkaline pH-activated K+ channel 2; 2P domain K+ channel Talk-2; TWIK-related acid-sensitive K+ channel 4; TASK-4 (KCNK17 TALK2, TASK4, UNQ5816/PRO19634) K+ channel subfamily K member 1; Inward rectifying K+ channel protein TWIK-1; K+ channel KCNO1 (KCNK1, HOHO1, KCNO1 TWIK1) K+ channel subfamily K member 2; outward rectifying K+ channel protein TREK-1; TREK-1 K+ channel subunit; Two pore K+ channel TPKC1; two pore domain K+ channel TREK-1 (KCNK2, TREK, TREK1) K+ channel subfamily K member 3; acid-sensitive K+ channel protein TASK-1; TWIK-related acid-sensitive K+ channel 1; Two pore K+ channel KT3.1 (KCNK3, TASK, TASK1) K+ channel subfamily K member 4; TWIK-related arachidonic acid-stimulated K+ channel protein; TRAAK; two pore K+ channel KT4.1 (KCNK4, TRAAK) K+ channel subfamily K member 5; acid-sensitive K+ channel protein TASK-2; TWIK-related acid-sensitive K+ channel 2 (KCNK5, TASK2) K+ channel subfamily K member 6; inward rectifying K+ channel protein TWIK-2; TWIK-originated similarity sequence (KCNK6, TOSS, TWIK2) K+ channel subfamily K member 7 (KCNK7) keratinocytes-associated protein 3 (KCP-3, KRTCAP3, KCP3, UNQ3066/PRO9898) lathosterol oxidase; C-5 sterol desaturase; delta(7)-sterol 5-desaturase; lathosterol 5-desaturase; sterol-C5-desaturase (SC5D, SC5DL) lens fiber membrane intrinsic protein (MP18, MP19, MP20, LIM2) leptin receptor gene-related protein; leptin receptor overlapping transcript protein; OB-R gene-related protein; OB-RGRP (LEPROT, LEPR, OBR) lipid phosphate phosphatase PPAPDC3 (phosphatidic acid phosphatase type 2 domain-containing protein 3, PPAPDC3, C9orf67) lysocardiolipin acyltransferase; acyl-CoA:lysocardiolipin acyltransferase 1; 1-AGP acyltransferase 8; 1-AGPAT 8 (LYCAT, LCLAT1, AGPAT8, ALCAT1, UNQ1849/PRO3579) lysosomal-associated transmembrane protein 4A (Golgi 4-transmembrane spanning transporter MTP, LAPTM4A, KIAA0108, LAPTM4, MTRP) lysosomal-associated transmembrane protein 4B (lysosome-associated transmembrane protein 4-beta, LAPTM4B) macoilin (transmembrane protein 57, TMEM57) MAL-like protein (protein BENE, MALL BENE) MARVEL domain-containing protein 1 (MARVELD1 MRVLDC1) MARVEL domain-containing protein 3 (MARVELD3, MRVLDC3) membrane-spanning 4-domains subfamily A member 10 (MS4A10) membrane-spanning 4-domains subfamily A member 12 (MS4A12) membrane-spanning 4-domains subfamily A member 3 (hematopoietic-specific transmembrane 4 protein, HTm4, CD20 antigen-like protein, MS4A3, CD20L, HTM4) membrane-spanning 4-domains subfamily A member 4A (four-span transmembrane protein 1, CD20 antigen-like 1, MS4A4A, 4SPAN1, CD20L1, MS4A4, HDCME31P) membrane-spanning 4-domains subfamily A member 5 (testis-expressed transmembrane 4 protein, CD20 antigen-like 2, MS4A5, CD20L2, TETM4) membrane-spanning 4-domains subfamily A member 6A (four-span transmembrane protein 3, CD20 antigen-like 3, MS4A6A, 4SPAN3, CD20L3, MS4A6, CDA01) membrane-spanning 4-domains subfamily A member 7 (CD20/FC-epsilon-RI-beta family member 4, four-span transmembrane protein 2, CD20 antigen-like 4, MS4A7, 4SPAN2, CD20L4, CFFM4) membrane-spanning 4-domains subfamily A member 8; four-span transmembrane protein 4; membrane-spanning 4-domains subfamily A member 8B (MS4A8, 4SPAN4, MS4A8B) MLN64 N-terminal domain homolog (STARD3 N-terminal-like protein, STARD3NL, MENTHO, UNQ855/PRO1864) myelin & lymphocyte protein; T-lymphocyte maturation-associated protein (MAL) myelin proteolipid protein; PLP; lipophilin (PLP1, PLP) neuronal membrane glycoprotein M6-a (GPM6A, M6a) neuronal membrane glycoprotein M6-b (GPM6B, M6b) p53 apoptosis effector related to PMP-22; keratinocyte-associated protein 1; KCP-1; P53-induced protein PIGPC1; transmembrane protein THW (PERP, KCP1, KRTCAP1, PIGPC1, THW) palmitoyltransferase ZDHHC14 (zinc finger DHHC domain-containing protein 144, DHHC-14, NEW1 domain-containing protein, NEW1CP, ZDHHC14) palmitoyltransferase ZDHHC15 (zinc finger DHHC domain-containing protein 15, DHHC-15, ZDHHC15) palmitoyltransferase ZDHHC16 (zinc finger DHHC domain-containing protein 16, DHHC-16, ZDHHC16) palmitoyltransferase ZDHHC18 (zinc finger DHHC domain-containing protein 18, DHHC-18, ZDHHC18) palmitoyltransferase ZDHHC19 (zinc finger DHHC domain-containing protein 19, DHHC-19, ZDHHC19) palmitoyltransferase ZDHHC20; zinc finger DHHC domain-containing protein 20; DHHC-20 (ZDHHC20) palmitoyltransferase ZDHHC21 (zinc finger DHHC domain-containing protein 21, DHHC-22, ZDHHC21) pannexin peripherin-2; retinal peripherin; retinal degeneration slow protein; tetraspanin-22; Tspan-22 (PRPH2, PRPH, RDS, TSPAN22) peroxisomal membrane protein 2; 22 kD peroxisomal membrane protein (PXMP2, PMP22) phosphatidylethanolamine N-methyltransferase; PEAMT (PEMT, PEMPT, PNMT) phosphatidylinositol N-acetylglucosaminyltransferase subunit C; phosphatidylinositol-glycan biosynthesis class C protein; PIG-C (PIGC, GPI2) plasmolipin; plasma membrane proteolipid (PLLP, PMLP, TM4SF11) PQ loop repeat-containing protein 3 (PQLC3, C2orf22) PRA1 family protein 2 (PRAF2) PRA1 family protein 3 (ARL-6-interacting protein 5, ADP-ribosylation- like factor 6-interacting protein 5, Aip-5, glutamate transporter EAAC1-interacting protein, GTRAP3-18, prenylated Rab acceptor protein 2, protein JWa, dermal papilla-derived protein 11, JM5, putative MAPK-activating protein PM27, cytoskeleton-related vitamin A-responsive protein, ARL6IP5, DERP11, JWA, PRA2, PRAF3, HSPC127) prenylated Rab acceptor protein 1 (PRA1 family protein 1, RABAC1, PRA1, PRAF1) presqualene diphosphate phosphatase (phosphatidic acid phosphatase type 2 domain-containing protein 2, PPAPDC2) protein C14orf83 (TMEM229B) protein COTE1 (FAM189B, C1orf2, COTE1) Protein FAM77C (FAM77C, NKAIN1) Protein jagunal homolog 1 (JAGN1) protein Mpv17; glomerulosclerosis protein MPV17, human homolog (MPV17) protein NKG7 (natural killer cell protein 7, G-CSF-induced gene 1 protein, protein GIG-1, NKG7, GIG1) protein orai-2 (transmembrane protein 142B, CAP-binding protein complex-interacting protein 2, TMEM142B, C7orf19, CBCIP2, ORAI2) protein SYS1 homolog (SYS1, C20orf169) protein-S-isoprenylcysteine O-methyltransferase; isoprenylcysteine carboxylmethyltransferase; prenylated protein carboxyl methyltransferase; PPMT; prenylcysteine carboxyl methyltransferase; pcCMT (ICMT, PCCMT) rhomboid domain-containing protein 1 (RHBDD1) sarcospan; K-ras oncogene-associated protein; Kirsten-ras-associated protein (SSPN, KRAG) secretory carrier-associated membrane protein 1; secretory carrier membrane protein 1 (SCAMP1, SCAMP) secretory carrier-associated membrane protein 2; secretory carrier membrane protein 2 (SCAMP2) secretory carrier-associated membrane protein 3; secretory carrier membrane protein 3 (SCAMP3, C1orf3, PROPIN1) secretory carrier-associated membrane protein 4 (secretory carrier membrane protein 4, SCAMP4) secretory carrier-associated membrane protein 5 (secretory carrier membrane protein 5, SCAMP5) short-chain dehydrogenase/reductase 3; DD83.1; retinal short-chain dehydrogenase/reductase 1; retSDR1 (DHRS3) sideroflexin-5 (SFXN5) Sn1-specific diacylglycerol lipase alpha (DGL-alpha, neural stem cell-derived dendrite regulator, DAGLA, C11orf11, KIAA0659, NSDDR) Sn1-specific diacylglycerol lipase beta (DGL-beta, KCCR13L, DAGLB) solute carrier family 25 member 10; mitochondrial dicarboxylate carrier (SLC25A10, DIC) solute carrier family 25 member 21; mitochondrial 2-oxodicarboxylate carrier (SLC25A21, ODC) solute carrier family 35 member E2 (SLC35E2) StAR-related lipid transfer protein 3; metastatic lymph node gene 64 protein; MLN 64; protein CAB1; START domain-containing protein 3; StARD3 (STARD3, CAB1, MLN64) synaptophysin-like protein 1 (pantophysin, SYPL1, SYPL) synaptophysin-like protein 2 (SYPL2) synaptophysin; major synaptic vesicle protein p38 (SYP) synaptoporin (SYNPR) T-cell lymphoma breakpoint associated target protein 1; protein FAM77B (TCBA1, FAM77B, NKAIN2) tetraspanin (transmembrane-4-superprotein) tetraspanin-9 (Tspan-9, tetraspan NET-5, TSPAN9, NET5) transmembrane 4 L6 family member 18 (TM4SF18) transmembrane 4 L6 family member 19 (TM4SF19) transmembrane 4 L6 family member 1; tumor-associated antigen L6; membrane component surface marker 1; M3S1 (TM4SF1, M3S1, TAAL6) transmembrane protein 107 (TMEM107) transmembrane protein 128 (TMEM128) transmembrane protein 140 (TMEM140) transmembrane protein 14B (TMEM14B) transmembrane protein 14C (TMEM14C C6orf53 HSPC194) transmembrane protein 17 (TMEM17) transmembrane protein 171 (TMEM171) transmembrane protein 176A (hepatocellular carcinoma-associated antigen 112, TMEM176A, HCA112) Transmembrane protein 176B (protein LR8, TMEM176B, LR8) transmembrane protein 179 (TMEM179, C14orf90) transmembrane protein 255A; protein FAM70A (TMEM255A, FAM70A) transmembrane protein 255B; protein FAM70B (TMEM255B, FAM70B) transmembrane protein 276 (TMEM276) transmembrane protein 35 (TMEM35) transmembrane protein 42 (TMEM42) transmembrane protein 50A (small membrane protein 1, TMEM50A, SMP1, UNQ386/PRO718) transmembrane protein 50B (HCV p7-transregulated protein 3, TMEM50B, C21orf4, UNQ167/PRO193) transmembrane protein 54 (beta-casein-like protein, protein CAC-1, TMEM54, BCLP, CAC1) transmembrane protein 80 (TMEM80) transmembrane protein 97 (protein MAC30, TMEM97, MAC30) UPF0504 protein (TMEM192) uroplakin-1a; UP1a; uroplakin Ia; UPIa; UPKa; tetraspanin-21; Tspan-21 (UPK1A, TSPAN21) uroplakin-1b; UP1b; uroplakin Ib; UPIb; tetraspanin-20; Tspan-20 (UPK1B TSPAN20) Vang-like protein 1 (Van Gogh-like protein 1, strabismus 2, loop-tail protein 2 homolog, LPP2, VANGL1, STB2) Vang-like protein 2 (Van Gogh-like protein 2, strabismus 1, loop-tail protein 1 homolog, VANGL2, KIAA1215, STB1) vesicle transport protein GOT1A (Golgi transport 1 homolog A, hGOT1b, GOLT1A, GOT1B) vesicle transport protein GOT1B (Golgi transport 1 homolog B, hGOT1a, NF-kappa-B-activating protein 470, GOLT1B, GOT1A) vesicle transport protein SFT2A (SFT2 domain-containing protein 1, pRGR1, SFT2D1) vesicle transport protein SFT2B (SFT2 domain-containing protein 2, SFT2D2) vesicle transport protein SFT2C (SFT2 domain-containing protein 3, SFT2D3) vesicle-trafficking protein SEC22a (SEC22 vesicle-trafficking protein homolog A, SEC22 vesicle-trafficking protein-like 2, SEC22A, SEC22L2) vesicle-trafficking protein SEC22c (SEC22 vesicle-trafficking protein homolog C, SEC22 vesicle-trafficking protein-like 3, SEC22C, SEC22L3, UNQ459/PRO784) vitamin K epoxide reductase complex subunit 1-like protein 1; VKORC1-like protein 1 (VKORC1L1) voltage-dependent Ca+2 channel gamma-1 (CACNG1, CACNLG) voltage-dependent Ca+2 channel gamma-2 (neuronal voltage-gated calcium channel gamma-2 subunit, CACNG2) voltage-dependent Ca+2 channel gamma-3 (neuronal voltage-gated calcium channel gamma-3 subunit, CACNG3) voltage-dependent Ca+2 channel gamma-4 (neuronal voltage-gated calcium channel gamma-4 subunit, CACNG4) voltage-dependent Ca+2 channel gamma-6 (neuronal voltage-gated calcium channel gamma-6 subunit, CACNG6) voltage-dependent Ca+2 channel gamma-7 (neuronal voltage-gated calcium channel gamma-7 subunit, CACNG7) voltage-gated hydrogen channel 1 (hydrogen voltage-gated channel 1, HV1, voltage sensor domain-only protein, HVCN1, VSOP, UNQ578/PRO1140) zinc finger protein 103; KF1; RING finger protein-103 (RNF103, ZNF103) zinc finger protein 370; palmitoyltransferase ZDHHC7; zinc finger DHHC domain-containing protein 7; DHHC-7 (ZDHHC7, ZNF370) zinc finger protein 372; palmitoyltransferase ZDHHC2; reduced expression associated with metastasis protein; Ream; reduced expression in cancer protein; rec; zinc finger DHHC domain-containing protein 2; DHHC-2 (ZDHHC2, REAM, REC, ZNF372) zinc finger protein 373; palmitoyltransferase ZDHHC3; protein DHHC1; zinc finger DHHC domain-containing protein 3; DHHC-3 (ZDHHC3, ZNF373, HSD49) zinc finger protein 375; palmitoyltransferase ZDHHC5; zinc finger DHHC domain-containing protein 5; DHHC-5 (ZDHHC5, KIAA1748, ZNF375) zinc finger protein 376; palmitoyltransferase ZDHHC6; transmembrane protein H4; zinc finger DHHC domain-containing protein 6; DHHC-6 (ZDHHC6, ZNF376) zinc finger protein 377; palmitoyltransferase ZDHHC1; DHHC domain-containing cysteine-rich protein 1; zinc finger DHHC domain-containing protein 1; DHHC-1 (ZDHHC1, C16orf1, ZNF377) zinc finger protein 378; palmitoyltransferase ZDHHC8; zinc finger DHHC domain-containing protein 8; DHHC-8 (ZDHHC8, KIAA1292, ZDHHCL1, ZNF378) zinc finger protein 379; palmitoyltransferase ZDHHC9; zinc finger DHHC domain-containing protein 9; DHHC-9; DHHC9; zinc finger protein 380 (ZDHHC9, CXorf11, ZDHHC10, ZNF379, ZNF380, CGI-89, UNQ261/PRO298) zinc finger protein 399; palmitoyltransferase ZDHHC11; zinc finger DHHC domain-containing protein 11; DHHC-11 (ZDHHC11, ZNF399) zinc finger protein 400; palmitoyltransferase ZDHHC12; zinc finger DHHC domain-containing protein 12; DHHC-12 (ZDHHC12, ZNF400, PSEC0008)

Properties

COMPARTMENT: cellular membrane MOTIF: cytoplasmic domain {N-TERMINAL} transmembrane domain {TM1} exoplasmic loop LOOP#: 1 transmembrane domain {TM2} cytoplasmic loop transmembrane domain {TM3} exoplasmic loop LOOP#: 2 transmembrane domain {TM4} cytoplasmic domain {C-TERMINAL}