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Translocase of outer membrane TOM70 (mitochondrial precursor proteins import receptor, TOMM70A, KIAA0719)
Function:
1) receptor that accelerates import of all mitochondrial precursor proteins
2) forms part of the receptor complex that consists of at least 8 different proteins
Structure:
1) belongs to the Tom70 family
2) contains 10 TPR repeats
Compartment: mitochondrial outer membrane
General
mitochondrial membrane protein
receptor
Properties
SIZE: MW = 67 kD
entity length = 608 aa
COMPARTMENT: mitochondria
MOTIF: MITOCHONDRIAL INTERMEMBRANE {1-8}
transmembrane domain {9-29}
tetratricopeptide repeat {114-147}
tetratricopeptide repeat {153-186}
tetratricopeptide repeat {294-327}
tetratricopeptide repeat {329-362}
tetratricopeptide repeat {367-400}
tetratricopeptide repeat {401-434}
tetratricopeptide repeat {440-475}
tetratricopeptide repeat {476-509}
tetratricopeptide repeat {511-544}
tetratricopeptide repeat {545-578}
Database Correlations
OMIM 606081
UniProt O94826
PFAM correlations
References
UniProt :accession O94826