Search
transglutaminase-1 gene (TGM1)
Related
transglutaminase-1, keratinocyte transglutaminase, epidermal transglutaminase, or transglutaminase-K
General
housekeeping gene
Properties
TEMPLATE-FOR: messenger RNA
TEMPLATE-FOR: transglutaminase-1
LOCUS: human chromosome-14 Q11.2
SIZE: entity length = 14.3 KB
entity length = 15 EXONS
MOTIF: AP1 site
NAME: AP1 site
SITE: -536
CCAAT box
SITE: -392
NUCLEOTIDE-SEQUENCE: DNA sequence
SEQUENCE-IS: GCCAAT
nuclear factor-1 [NF1] site
NAME: nuclear factor-1 [NF1] site
SITE: -160
NUCLEOTIDE-SEQUENCE: consensus
consensus
SP1-binding site
SITE: -87
FOR-BINDING-OF: transcription factor Sp1
SP1-binding site
SITE: -61
FOR-BINDING-OF: transcription factor Sp1
transcriptional start site
exon (15)
intron (14)
transcriptional termination site
References
- Saunders NA, Bernacki SH, Vollberg TM, Jetten AM.
Regulation of transglutaminase type I expression in squamous
differentiating rabbit tracheal epithelial cells and human
epidermal keratinocytes: effects of retinoic acid and phorbol
esters.
Mol Endocrinol. 1993 Mar;7(3):387-98.
PMID: 8097865
- Yamanishi K, Inazawa J, Liew FM, Nonomura K, Ariyama T,
Yasuno H, Abe T, Doi H, Hirano J, Fukushima S.
Structure of the gene for human transglutaminase 1.
J Biol Chem. 1992 Sep 5;267(25):17858-63.
PMID: 1381356