transglutaminase (protein-glutamine:amine gamma-glutamyltransferase)

Catalyzes condensation of epsilon amino group of lysine with gamma-carboxyl group of glutamine residues. Glutamine may be used instead of lysine, i.e. factor XIIIa??? Stable intermolecular crosslinks form.

Specific

coagulation factor XIIIa; transglutaminase transglutaminase 3-like (protein-glutamine gamma-glutamyltransferase 3-like, transglutaminase 6, TGM6) transglutaminase 7 or protein-glutamine gamma-glutamyltransferase Z transglutaminase-1, keratinocyte transglutaminase, epidermal transglutaminase, or transglutaminase-K transglutaminase-2 (tissue transglutaminase, tranglutaminase-C, TGM2) transglutaminase-3 (tranglutaminase-E, E3, TGM3) transglutaminase-4 [prostate] (fibrinoligase, prostate transglutaminase, TGP, prostate-specific transglutaminase, TGM4) transglutaminase-5 (TGM5, protein-glutamine gamma-glutamyltransferase X)

General

Ca+2 binding protein glutamyltransferase regulatory molecule

Properties

STATE: Inactive MOTIF: active site MOTIF: cysteine residue Ca+2-binding site