transcription initiation factor TFIID subunit 3; 140 kD TATA box-binding protein-associated factor; TBP-associated factor 3; transcription initiation factor TFIID 140 kD subunit; TAF(II)140; TAF140; TAFII-140; TAFII140 (TAF3)

Function: 1) component of TFIID complex 2) interacts with TAF10 via histone fold 3) interacts with TAF13, TBP, SAP130 & GCN5L2 Structure: - belongs to the TAF3 family - contains 1 PHD-type zinc finger Compartment: nucleus

General

nuclear protein phosphoprotein protein subunit zinc finger protein

Properties

SIZE: entity length = 929 aa MW = 104 kD COMPARTMENT: cell nucleus MOTIF: glutamate-rich region {136-141} MOTIF: glutamate residue (SEVERAL) glutamate-rich region {163-168} MOTIF: glutamate residue (SEVERAL) Ser phosphorylation site {S183} Ser phosphorylation site {S199} Ser phosphorylation site {S229} Ser phosphorylation site {S236} Ser phosphorylation site {S243} Ser phosphorylation site {S267} Ser phosphorylation site {S291} Ser phosphorylation site {S297} Ser phosphorylation site {S301} Thr phosphorylation site {T364} Ser phosphorylation site {S410} Ser phosphorylation site {S411} Ser phosphorylation site {S413} Ser phosphorylation site {S415} Thr phosphorylation site {T501} lysine-rich region {507-746} MOTIF: lysine residue (SEVERAL) proline-rich region SITE: 779-833 MOTIF: proline residue (SEVERAL) Zn finger PHD-type NAME: Zn finger PHD-type SITE: 865-915 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 606576 UniProt Q5VWG9 PFAM correlations Entrez Gene 83860 Kegg hsa:83860

References

UniProt :accession Q5VWG9