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transcription initiation factor TFIID subunit 2; 150 kD cofactor of initiator function; RNA polymerase II TBP-associated factor subunit B; TBP-associated factor 150 kDa; transcription initiation factor TFIID 150 kD subunit; TAF(II)150; TAFII-150; TAFII150 (TAF2, CIF150, TAF2B)
Function:
1) stabilizes TFIID binding to core promoter
2) interacts with TAF2C1
Compartment: nucleus
Expression: expressed in all tissues
General
nuclear protein
phosphoprotein
protein subunit
Properties
SIZE: entity length = 1199 aa
MW = 137 kD
COMPARTMENT: cell nucleus
MOTIF: lysine-rich region {600-603}
MOTIF: lysine residue (SEVERAL)
histidine-rich region {1143-1171}
MOTIF: histidine residue (SEVERAL)
lysine-rich region {1155-1178}
MOTIF: lysine residue (SEVERAL)
Ser phosphorylation site {S1194}
Ser phosphorylation site {S1196}
Ser phosphorylation site {S1198}
Database Correlations
OMIM 604912
UniProt Q6P1X5
Pfam PF01433
Entrez Gene 6873
Kegg hsa:6873
References
UniProt :accession Q6P1X5
Component-of
TFTC-HAT complex (TATA-binding protein-free TAF complex, TBP-free TAFII complex, TFTC)