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transcription initiation factor TFIID subunit 2; 150 kD cofactor of initiator function; RNA polymerase II TBP-associated factor subunit B; TBP-associated factor 150 kDa; transcription initiation factor TFIID 150 kD subunit; TAF(II)150; TAFII-150; TAFII150 (TAF2, CIF150, TAF2B)

Function: 1) stabilizes TFIID binding to core promoter 2) interacts with TAF2C1 Compartment: nucleus Expression: expressed in all tissues

General

nuclear protein phosphoprotein protein subunit

Properties

SIZE: entity length = 1199 aa MW = 137 kD COMPARTMENT: cell nucleus MOTIF: lysine-rich region {600-603} MOTIF: lysine residue (SEVERAL) histidine-rich region {1143-1171} MOTIF: histidine residue (SEVERAL) lysine-rich region {1155-1178} MOTIF: lysine residue (SEVERAL) Ser phosphorylation site {S1194} Ser phosphorylation site {S1196} Ser phosphorylation site {S1198}

Database Correlations

OMIM 604912 UniProt Q6P1X5 Pfam PF01433 Entrez Gene 6873 Kegg hsa:6873

References

UniProt :accession Q6P1X5

Component-of

TFTC-HAT complex (TATA-binding protein-free TAF complex, TBP-free TAFII complex, TFTC)