transcription factor Sp5 (SP5)

Function: - binds to GC boxes promoters elements - transcriptional activator - role in coordination of changes in transcription required to generate pattern in developing embryo Compartment: nucleus Structure: - belongs to the Sp1 C2H2-type zinc-finger protein family - contains 3 C2H2-type zinc fingers

General

C2H2 type zinc finger protein DNA-binding protein transcription factor (TF)

Properties

SIZE: MW = 42 kD entity length = 398 aa COMPARTMENT: cell nucleus MOTIF: proline-rich region SITE: 164-173 MOTIF: proline residue (SEVERAL) alanine-rich region {224-235} MOTIF: alanine residue (SEVERAL) Zn finger C2H2-type SITE: 296-320 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 326-350 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 356-378 EFFECTOR-BOUND: Zn+2

Database Correlations

UniProt Q6BEB4 Pfam PF00096

References

UniProt :accession Q6BEB4