transcription factor SL1/TIFIB complex

Function: 1) assembly of the preinitiation complex 2) interaction of SL1/TIFIB subunits with TBP excludes interaction with transcription factor IID (TFIID) subunits 3) this mutually exclusive binding directs the formation of promoter & RNA polymerase-selective TBP-TAF complexes Structure: - consists of: TBP, TAF1A, TAF1B & TAF1C

Properties

COMPARTMENT: cell nucleus SUBUNITS: TATA-box-binding protein COMPARTMENT: cell nucleus MOTIF: glutamine-rich region {55-95} MOTIF: glutamine residue (SEVERAL) consensus repeat {165-241} consensus repeat {255-332} TATA box-binding protein-associated factor RNA polymerase 1 subunit A COMPARTMENT: cell nucleus TATA box-binding protein-associated factor RNA polymerase 1 subunit B COMPARTMENT: cell nucleus TATA box-binding protein-associated factor RNA polymerase 1 subunit C COMPARTMENT: cell nucleus

References

UniProt :accession Q14691, Q15573

Components

TATA box-binding protein-associated factor RNA polymerase 1 subunit A (TATA box-binding protein-associated factor 1C, TBP-associated factor 1A, TBP-associated factor RNA polymerase I 48 kD, TAFI48, TAF1A) TATA box-binding protein-associated factor RNA polymerase 1 subunit B (TATA box-binding protein-associated factor 1B, TBP-associated factor 1B, TBP-associated factor RNA polymerase I 63 kD, TAFI63, TAF1B) TATA box-binding protein-associated factor RNA polymerase 1 subunit C (TATA box-binding protein-associated factor 1C, TBP-associated factor 1C, TBP-associated factor RNA polymerase I 110 kD, TAFI110, TAF1C) TATA-box-binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; transcription initiation factor TFIID TBP subunit; p38TFIID; p38tau (TBP, GTF2D1, TF2D, TFIID)