transcription factor PML-X or My1 protein

PROBABLE TRANSCRIPTION FACTOR PML-X.

General

DNA-binding protein proto oncogene protein ring finger protein transcription factor (TF)

Properties

SIZE: entity length = 882 aa MW = 98 kD COMPARTMENT: cytoplasm cell nucleus FORM: transcription factor pml x MOTIF: proline-rich region SITE: 3-46 MOTIF: proline residue (SEVERAL) Ser phosphorylation site {S8} RING-finger {57-92} MOTIF: Zn+2-binding site SITE: 57-57 Zn+2-binding site SITE: 60-60 Zn+2-binding site SITE: 72-72 Zn+2-binding site SITE: 74-74 Zn+2-binding site SITE: 77-77 Zn+2-binding site SITE: 80-80 Zn+2-binding site SITE: 88-88 Zn+2-binding site SITE: 91-91 EFFECTOR-BOUND: Zn+2 FOR-BINDING-OF: DNA motif zinc finger B box SITE: 124-166 EFFECTOR-BOUND: Zn+2 zinc finger B box SITE: 183-236 EFFECTOR-BOUND: Zn+2 coiled coil {228-253} Breakpoint {394-395} Ser phosphorylation site {S403} nuclear translocation signal {476-490} Ser phosphorylation site {S504} Ser phosphorylation site {S505} Ser phosphorylation site {S512} Ser phosphorylation site {S518} Ser phosphorylation site {S527} Ser phosphorylation site {S530} Ser phosphorylation site {S535} Breakpoint {552-553} Ser phosphorylation site {S560} Ser phosphorylation site {S561} Ser phosphorylation site {S562} Ser phosphorylation site {S565}

Database Correlations

OMIM 102578 UniProt P29590 PFAM correlations Entrez Gene 5371 Kegg hsa:5371