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transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1, CRTR-1, Transcription factor LBP-9, TFCP2L1, CRTR1, LBP9)
Function:
- transcriptional suppressor
- may suppress UBP1-mediated transcriptional activation
- modulates placental expression of CYP11A1
Structure: belongs to the grh/CP2 family. CP2 subfamily
Compartment: nucleus
Expression:
- highly expressed in placental JEG-3 cells
- very low levels of expression in non-steroidogenic cells
- no expression was seen in adrenal NCI-H295A cells or in adrenal tissue
General
transcriptional silencer (transcriptional repressor)
Properties
SIZE: MW = 55 kD
entity length = 479 aa
COMPARTMENT: cell nucleus
MOTIF: silencer element
SITE: 1-52
Database Correlations
UniProt Q9NZI6
Pfam PF04516
References
UniProt :accession Q9NZI6