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transcription factor 25 (nuclear localized protein 1, TCF25, KIAA1049, NULP1, FKSG26)
Function:
- transcriptional repressor
- can repress transcription of SRF in vitro
- role in heart development (putative)
Structure:
- C-terminal region mediates transcriptional repression
- belongs to the NULP1 family
Compartment: nucleus
Expression:
- in the embryo, widely expressed with highest levels in brain
- in the adult, highest expression is found in the heart
General
transcriptional silencer (transcriptional repressor)
Properties
SIZE: MW = 77 kD
entity length = 676 aa
COMPARTMENT: cell nucleus
Database Correlations
UniProt Q9BQ70
Pfam PF04910
References
UniProt :accession Q9BQ70