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transcription factor 15; bHLH-EC2 protein; paraxis (TCF15, BHLHEC2)
Function:
- may function as an early transcriptional regulator, involved in the patterning of the mesoderm & in lineage determination of cell types derived from the mesoderm
- efficient DNA binding requires dimerization with another bHLH protein (putative)
Structure: contains 1 basic helix-loop-helix (bHLH) domain
Compartment: nucleus (putative)
General
basic helix loop helix (bHLH) family transcription factor
Properties
SIZE: entity length = 199 aa
MW = 21 kD
COMPARTMENT: cell nucleus
MOTIF: glycine-rich region {52-66}
DNA-binding motif
SITE: 72-84
helix-loop-helix
NAME: helix-loop-helix
SITE: 85-125
FOR-BINDING-VIA: helix-loop-helix
Database Correlations
OMIM 601010
UniProt Q12870
Pfam PF00010
Kegg hsa:6939
References
UniProt :accession Q12870