transcription elongation factor A protein 2 (transcription elongation factor S-II protein 2, transcription elongation factor TFIIS.i, TCEA2 TFIIS.i)

Function: - facilitates RNA polymerase 2 transcription elongation past template-encoded arresting sites - arresting sites trap some of the elongating RNA polymerase, resulting in block of transcription - cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'terminus. Expression: testis & ovary-specific

General

DNA-binding protein transcription elongation factor zinc finger protein

Properties

SIZE: MW = 34 kD entity length = 299 aa COMPARTMENT: cell nucleus MOTIF: Zn ribbon SITE: 261-299 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 604784 UniProt Q15560 PFAM correlations Kegg hsa:1021

References

UniProt :accession Q15560