transcriptional silencer (transcriptional repressor)

transcription factor that represses or silences expression of a gene or genes

Specific

achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1, ASCL3, HASH3, SGN1) arginine-glutamic acid dipeptide repeats protein (atrophin-1-like protein, atrophin-1-related protein, RERE, ARG, ARP, ATN1L, KIAA0458) aryl hydrocarbon receptor repressor (AhR repressor, AhRR, AHRR, KIAA1234) AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B, histone deacetylase complex subunit SAP180, 180 kD Sin3-associated polypeptide, Sin3-associated polypeptide p180, Retinoblastoma-binding protein 1-like 1, breast cancer-associated antigen BRCAA1, ARID4B, BRCAA1, RBBP1L1, RBP1L1, SAP180) Bcl-2-associated transcription factor 1 (Btf, BCLAF1, KIAA0164) BCL-6 corepressor (BCoR, KIAA1575) BCoR-like protein 1 (BCL6 corepressor-like protein 1, BCoR-L1, BCORL1) breast cancer metastasis-suppressor 1 (BRMS1) BTB/POZ domain-containing protein 14B; nucleus accumbens-1; NAC-1 (BTBD14B, NAC1, NACC1) C-myc promoter-binding protein (DENN domain-containing protein 4A, DENND4A, IRLB, MYCPBP) calsenilin; Kv channel-interacting protein 3; KChIP3; A-type K+ channel modulatory protein 3; DRE-antagonist modulator; DREAM (KCNIP3, CSEN, DREAM, KCHIP3) cartilage homeoprotein 1 (CART1, ALX1) CBF1-interacting corepressor; recepin (CIR, CIR1) CCR4-NOT transcription complex subunit 1 (negative regulator of transcription subunit 1 homolog, NOT1H, hNOT1, CCR4-associated factor 1, CNOT1, CDC39, KIAA1007, NOT1, AD-005) CCR4-NOT transcription complex subunit 4; CCR4-associated factor 4; E3 ubiquitin-protein ligase CNOT4; transcriptional repressor NOT4Hp (CNOT4, NOT4) cell division cycle-associated 7-like protein (protein JPO2, transcription factor RAM2, CDCA7L, HR1, JPO2 R1) cellular nucleic acid-binding protein; CNBP; zinc finger protein 9 (CNBP, RNF163, ZNF9) class B basic helix-loop-helix protein 3; bHLHB3; differentially expressed in chondrocytes protein 2; hDEC2; enhancer-of-split & hairy-related protein 1; SHARP-1 (BHLHB3, BHLHE41) Dr1-associated corepressor (Dr1-associated protein 1, negative cofactor 2 alpha, NC2 alpha, DRAP1) fer3-like protein (nephew of atonal 3, basic helix-loop-helix protein N-twist, neuronal twist, FERD3L, NATO3, NTWIST) Fez family zinc finger protein 1 (zinc finger protein 312B, FEZF1, FEZ, ZNF312B) Fez family zinc finger protein 2 (forebrain embryonic zinc finger-like protein 2, zinc finger protein Fez-like, zinc finger protein 312, FEZF2, FEZL, ZNF312, FKSG36) fibrinogen silencer-binding protein (FSBP) forkhead box protein S1; forkhead-like 18 protein; forkhead-related transcription factor 10; FREAC-10 (FOXS1 FKHL18 FREAC10) gamma-interferon-inducible protein 16; Ifi-16; interferon-inducible myeloid differentiation transcriptional activator (IFI16, IFNGIP1) hairy & enhancer of split-related protein HELT; HES/HEY-like transcription factor (HELT) hairy/enhancer-of-split related with YRPW motif 2 (cardiovascular helix-loop-helix factor 1, hairy & enhancer of split-related protein 2, HESR-2, hairy-related transcription factor 2, HES-related repressor protein 2, protein gridlock homolog, HEY2, CHF1, GRL, HERP, HERP1, HRT2) hairy/enhancer-of-split related with YRPW motif-like protein (hHeyL, hairy-related transcription factor 3, hHRT3, HEYL HRT3) histone-lysine N-methyltransferase EZH1; ENX-2; enhancer of zeste homolog 1 (EZH1, KIAA0388) histone-lysine N-methyltransferase EZH2; ENX-1; enhancer of zeste homolog 2; lysine N-methyltransferase 6 (EZH2, KMT6) HMG box-containing protein 1 (HMG box transcription factor 1, high mobility group box transcription factor 1, HBP1) homeobox protein Nkx-3.2; Bagpipe homeobox protein homolog 1; homeobox protein NK-3 homolog B (NKX3-2, BAPX1, NKX3B) homeobox protein TGIF2; 5'-TG-3'-interacting factor 2; TGF-beta-induced transcription factor 2; TGFB-induced factor 2 (TGIF2) Id (inhibition of differentiation/DNA binding) helix loop helix protein interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1, IRF-2BP1, IRF2BP1) interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2, IRF-2BP2, IRF2BP2) Krueppel-like factor 10; EGR-alpha; transforming growth factor-beta-inducible early growth response protein 1; TGFB-inducible early growth response protein 1; TIEG-1 (KLF10, TIEG, TIEG1) Krueppel-like factor 11; transforming growth factor-beta-inducible early growth response protein 2; TGFB-inducible early growth response protein 2; TIEG-2 (KLF11, FKLF, TIEG2) Krueppel-like factor 12; transcriptional repressor AP-2rep (KLF12, AP2REP, HSPC122) ligand-dependent corepressor; LCoR; Mblk1-related protein 2 (LCOR, KIAA1795, MLR2) MAD protein; MAX dimerizer; MAX dimerization protein 1 (MXD1, MAD) Max dimerization protein 4; Max dimerizer 4; class C basic helix-loop-helix protein 12; bHLHc12; Max-associated protein 4; Max-interacting transcriptional repressor MAD4 (MXD4, BHLHC12, MAD4) Max-binding protein MNT (protein ROX, Myc antagonist MNT, MNT, ROX) Max-interacting transcriptional repressor MAD3 (Max-associated protein 3, MAX dimerization protein 3, Myx, MXD3, MAD3) mesoderm induction early response protein 1 (Mi-er1, hmi-er1, early response 1, Er1, MIER1, KIAA1610) mesoderm induction early response protein 2 (Mi-er2, MIER2, KIAA1193) mesoderm induction early response protein 3 (Mi-er3, MIER3) methyl-CpG-binding domain protein 3-like 1 (MBD3-like 1, MBD3L1, MBD3L) mSin3A corepressor complex Msx2-interacting protein (SPEN homolog, SMART/HDAC1-associated repressor protein, SPEN, KIAA0929, MINT, SHARP) musculin; activated B-cell factor 1; ABF-1; class A basic helix-loop-helix protein 22; bHLHa22 (MSC, ABF1, BHLHA22) Myb-related protein p42POP; partner of profilin (P42POP, MYPOP) myelin expression factor 2 (MyEF-2, MST156, MYEF2 KIAA1341) N-cor repressor complex NF-kappa-B-repressing factor; NFkB-repressing factor; protein ITBA4; transcription factor NRF (NKRF, ITBA4, NRF) NGFI-A-binding protein 1 (EGR-1-binding protein 1, transcriptional regulatory protein p54, NAB1) NGFI-A-binding protein 2; EGR-1-binding protein 2; melanoma-associated delayed early response protein; MADER protein (NAB2, MADER) nuclear factor interleukin-3 regulated protein (E4 promoter binding-protein 4, interleukin-3 promoter transcriptional activator, transcriptional activator NF-IL3A, interleukin-3 binding-protein 1, NFIL3, E4BP4, IL3BP1) nuclear receptor corepressor (N-COR) nuclear receptor-interacting factor 3; centromere protein R; CENP-R; beta-3-endonexin; integrin beta-3-binding protein (ITGB3BP, CENPR, NRIF3) nuclease-sensitive element-binding protein 1; Y-box-binding protein 1; Y-box transcription factor; YB-1; CCAAT-binding transcription factor I subunit A; CBF-A; enhancer factor I subunit A; EFI-A; DNA-binding protein B; DBPB (YBX1, NSEP1, YB1) paired amphipathic helix protein sin3a; murine yeast transcription repressor Sin3 homolog; transcriptional corepressor Sin3a; histone deacetylase complex subunit Sin3a (SIN3A, mSin3A) paired amphipathic helix protein sin3b; histone deacetylase complex subunit sin3b; transcriptional corepressor sin3b (SIN3B, KIAA0700, msin3B) penicillinase repressor PHD finger protein 12; PHD factor 1; Pf1 (PHF12, KIAA1523) poly(U)-binding-splicing factor PUF60 (60 kD poly(U)-binding-splicing factor, FUSE-binding protein-interacting repressor, FBP-interacting repressor, siah-binding protein 1, Siah-BP1, Ro-binding protein 1, RoBP1, PUF60, FIR, ROBPI, SIAHBP1) Polycomb group multiprotein BCOR complex (PcG BCOR complex) polycomb group RING finger protein 2; DNA-binding protein mel-18; RING finger protein 110; zinc finger protein 144 (PCGF2, MEL18, RNF110, ZNF144) polycomb group RING finger protein 6 (RING finger protein 134, Mel18 & Bmi1-like RING finger, PCGF6, MBLR, RNF134) POU domain, class 3, transcription factor 1; octamer-binding protein 6; Oct-6; octamer-binding transcription factor 6; OTF-6; POU domain transcription factor SCIP (POU3F1, OCT6, OTF6) PRKC apoptosis WT1 regulator protein; prostate apoptosis response 4 protein; par-4 (PAWR PAR4) prohibitin-2; B-cell receptor-associated protein BAP37; repressor of estrogen receptor activity; D-prohibitin (PHB2, REA, BAP) protein capicua homolog (CIC, KIAA0306) protein EMSY (EMSY, C11orf30, GL002) Protein strawberry notch homolog 2 (SBNO2, KIAA0963) RE1-silencing transcription factor (neural-restrictive silencer factor, X2 box repressor, REST, NRSF, XBR) REST corepressor 3 ( RCOR3, KIAA1343) SET & MYND domain-containing protein 1 (SMYD1) sin3 repressor complex something about silencing protein 10; disrupter of silencing SAS10; charged amino acid-rich leucine zipper 1 (CRLZ1, SAS10, UTP3) suppression of tumorigenicity protein 18 (zinc finger protein 387, ST18, KIAA0535, ZNF387) T-box transcription factor TBX3; T-box protein 3 (TBX3) THAP domain-containing protein 7 (THAP7) transcription factor 25 (nuclear localized protein 1, TCF25, KIAA1049, NULP1, FKSG26) transcription factor 9; GC-rich sequence DNA-binding factor; GCF; GC-rich sequence DNA-binding factor (TCF9, GCFC2, C2orf3) transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1, CRTR-1, Transcription factor LBP-9, TFCP2L1, CRTR1, LBP9) transcription factor E4F1 (E3 ubiquitin-protein ligase E4F1, E4F transcription factor 1, transcription factor E4F, p120E4F, p50E4F, E4F1, E4F) transcription factor HES-1; class B basic helix-loop-helix protein 39; bHLHb39; Hairy & enhancer of split 1; Hairy homolog; Hairy-like protein; hHL (HES1, BHLHB39, HL, HRY) transcription factor HES-2 (hairy & enhancer of split 2, HES2) transcription factor HES-3 (hairy & enhancer of split 3) transcription factor HES-5 (Hairy & enhancer of split 5, HES5) transcription factor HES-7 (hairy & enhancer of split 7, bHLH factor Hes7, HES7) transcriptional repressor CTCF; 11-zinc finger protein; CCCTC-binding factor; CTCFL paralog (CTCF) transcriptional repressor CTCFL (CCCTC-binding factor, Brother of the regulator of imprinted sites, zinc finger protein CTCF-T, CTCF paralog, CTCFL BORIS) transcriptional repressor NF-X1; nuclear transcription factor, X box-binding protein 1 (NFX1, NFX2) transcriptional repressor p66 alpha (Hp66alpha, GATA zinc finger domain-containing protein 2A, GATAD2A) transcriptional repressor protein YY1; Yin & yang 1; YY-1; delta transcription factor; NF-E1 (YY1) transcriptional repressor scratch 1; Scratch homolog 1 zinc finger protein; SCRT; Scratch 1; hScrt (SCRT1) transcriptional repressor scratch 2; Scratch homolog 2 zinc finger protein (SCRT2) transducin-like enhancer protein 6 (TLE6) TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2, Tsc-22-like protein THG-1, TSC22D4, TILZ2) YY1-associated factor 2 (YAF2) zinc finger & BTB domain-containing protein 23; zinc finger protein 336; GDNF-inducible zinc finger protein 1 (GZF1, ZBTB23, ZNF336) zinc finger protein 133; zinc finger protein 150 (ZNF133, ZNF150) zinc finger protein 136 (ZNF136) zinc finger protein 138 (ZNF138) zinc finger protein 140 (ZNF140) zinc finger protein 141 (ZNF141, D4S90) zinc finger protein 148; zinc finger DNA-binding protein 89; transcription factor ZBP-89 (ZNF148, ZBP89) zinc finger protein 161 homolog; Zfp-161; zinc finger protein 5; HZF5; zinc finger & BTB domain-containing protein 14 (ZFP161, ZBTB14) zinc finger protein 174; AW-1; zinc finger & SCAN domain-containing protein 8 (ZNF174, ZSCAN8) zinc finger protein 202; zinc finger protein with KRAB & SCAN domains 10 (ZNF202, ZKSCAN10) zinc finger protein 238; 58 kD repressor protein; transcriptional repressor RP58; translin-associated zinc finger protein 1; TAZ-1; zinc finger & BTB domain-containing protein 18; zinc finger protein C2H2-171 (ZNF238, RP58, TAZ1, ZBTB18) zinc finger protein 274; neurotrophin receptor-interacting factor homolog; zinc finger protein HFB101; zinc finger protein with KRAB & SCAN domains 19; zinc finger protein zfp2; Zf2 (ZNF274, ZKSCAN19, SP2114) zinc finger protein 281; GC-box-binding zinc finger protein 1; transcription factor ZBP-99; zinc finger DNA-binding protein 99 (ZNF281, GZP1, ZBP99) zinc finger protein 282; HTLV-I U5RE-binding protein 1; HUB-1 (ZNF282 HUB1) zinc finger protein 300 (ZNF300) zinc finger protein 328; zinc finger protein 606 (ZNF606, KIAA1852, ZNF328) zinc finger protein 354C; kidney, ischemia, & developmentally-regulated protein 3; hKID3 (ZNF354C, KID3) zinc finger protein 366 (ZNF366) zinc finger protein 382; KRAB/zinc finger suppressor protein 1; KS1; multiple zinc finger & krueppel-associated box protein KS1 (ZNF382) zinc finger protein 396; zinc finger & SCAN domain-containing protein 14 (ZNF396, ZSCAN14) zinc finger protein 503 (ZNF503) zinc finger protein 57 homolog (Zfp-57, zinc finger protein 698, ZFP57, C6orf40, ZNF698) zinc finger protein 85; zinc finger protein HPF4; HTF1 (ZNF85) zinc finger protein Eos; Ikaros family Zn+2 finger protein 4 (IKZF4, KIAA1782, ZNFN1A4, zinc finger protein-1A-4 ) zinc finger protein Gfi-1; growth factor independent protein 1; zinc finger protein 163 (GFI1, ZNF163) zinc finger protein SNAI3 (protein snail homolog 3, zinc finger protein 293) (SNAI3 ZNF293)

Properties

COMPARTMENT: cell nucleus