transcriptional repressor p66 alpha (Hp66alpha, GATA zinc finger domain-containing protein 2A, GATAD2A)

Function: 1) transcriptional repressor 2) binds MBD2 & MBD3 3) component of a complex containing MBD2, HDAC1 &/or HDAC2 Structure: - contains 1 GATA-type zinc finger Compartment: nucleus, nuclear speckle Alternative splicing: named isoforms=2 Expression: ubiquitous, both in fetal & adult tissues

General

phosphoprotein transcriptional silencer (transcriptional repressor) zinc finger protein

Properties

SIZE: MW = 68 kD entity length = 633 aa COMPARTMENT: cell nucleus MOTIF: Ser phosphorylation site {S100} Ser phosphorylation site {S107} Ser phosphorylation site {S114} coiled coil {139-174} Zn finger GATA-type SITE: 411-464 EFFECTOR-BOUND: Zn+2

Database Correlations

UniProt Q86YP4 Pfam PF00320

References

UniProt :accession Q86YP4