trace amine receptor 5; TaR-5; G protein-coupled receptor GPR102 (TRAR5, TAAR8)

Function: - orphan receptor - could be a receptor for trace amines Structure: belongs to the G-protein coupled receptor 1 family Compartment: cell membrane Expression: - expressed in kidney & amygdala - not expressed in other tissues or brain regions tested

General

glycoprotein G-protein coupled receptor; serpentine receptor

Properties

SIZE: MW = 38 kD entity length = 342 aa COMPARTMENT: cellular membrane MOTIF: exoplasmic domain {1-31} MOTIF: N-glycosylation site {N4} N-glycosylation site {N18} transmembrane domain {32-52} cytoplasmic loop {53-67} transmembrane domain {68-88} exoplasmic loop {89-111} MOTIF: cysteine residue {C104} MODIFICATION: cysteine residue {C189} transmembrane domain {112-132} cytoplasmic loop {133-146} transmembrane domain {147-167} exoplasmic loop {168-195} MOTIF: cysteine residue {C189} MODIFICATION: cysteine residue {C104} transmembrane domain {196-216} cytoplasmic loop {217-258} transmembrane domain {259-279} exoplasmic loop {280-280} transmembrane domain {281-301} cytoplasmic domain {302-342}

Database Correlations

OMIM 606927 UniProt Q969N4 Pfam PF00001 Kegg hsa:8355

References

UniProt :accession Q969N4