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cysteine-rich secretory protein 2; CRISP-2; testis-specific protein TPX-1; cancer/testis antigen 36; CT36 (CRISP2, GAPDL5, TPX1)
Function:
- may regulate Ca+2 fluxes during sperm capacitation
Structure: belongs to the CRISP family
Compartment: secreted (probable)
Expression: testis & epididymis
General
phosphoprotein
secreted protein
Properties
SIZE: entity length = 243 aa
MW = 27 kD
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-21}
Thr phosphorylation site {T181}
Tyr phosphorylation site {Y183}
Thr phosphorylation site {T187}
cysteine residue {C189}
MODIFICATION: cysteine residue {C196}
cysteine residue {C192}
MODIFICATION: cysteine residue {C201}
cysteine residue {C196}
MODIFICATION: cysteine residue {C189}
cysteine residue {C201}
MODIFICATION: cysteine residue {C192}
cysteine residue {C205}
MODIFICATION: cysteine residue {C238}
cysteine residue {C214}
MODIFICATION: cysteine residue {C232}
cysteine residue {C223}
MODIFICATION: cysteine residue {C236}
cysteine residue {C232}
MODIFICATION: cysteine residue {C214}
cysteine residue {C236}
MODIFICATION: cysteine residue {C223}
cysteine residue {C238}
MODIFICATION: cysteine residue {C205}
Database Correlations
OMIM 187430
UniProt P16562
PFAM correlations
Entrez Gene 7180
Kegg hsa:7180
References
- UniProt :accession P16562
- Prosite :accession PS01009
- Prosite :accession PS01010