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total red cell volume
Indications:
- evaluation of polycythemia Procredure:
- Cr-51 labeled erythrocytes are used to measure red cell mass
- I-125 labed albumin is used to measure plasma volume; hematocrit is measured with a Coulter counter; total red cell volume is calculated (approximation)
- hct = red cell volume/ (plasma volume + red cell volume)
- hct x (plasma volume + red cell volume) = red cell volume
- red cell volume x (1 - hct) = hct x plasma volume
- red cell volume = (hct x plasma volume) / (1 - hct)
General
clinical hematology test
nuclear medicine
References
- Fairbanks VF et al
Measurement of Blood Volume and Red Cell Mass:
Re-examination of 51Cr and 125I Methods
Blood Cells, Molecules, and Diseases (1996) 22(15): 169-186
http://www.scripps.edu/bcmd/pdfarea/issue_15_96/fairbanks.pdf
Component-of
blood volume