torsin-1B; torsin family 1 member B (TOR1B, DQ1, FKSG18)

Function: - may serve as a molecular chaperone assisting in the proper folding of secreted &/or membrane proteins Structure: - belongs to the clpA/clpB family, Torsin subfamily Compartment: - endoplasmic reticulum lumen (putative) Expression: - widely expressed - low levels in brain - not detected in fetal brain

General

glycoprotein torsin

Properties

SIZE: entity length = 336 aa MW = 38 kD COMPARTMENT: endoplasmic reticulum MOTIF: signal sequence {1-24} N-glycosylation site {N64} ATP-binding site NAME: ATP-binding site SITE: 109-116 N-glycosylation site {N165}

Database Correlations

OMIM 608050 UniProt O14657 Pfam PF06309 Entrez Gene 27348 Kegg hsa:27348

References

UniProt :accession O14657