TM2 domain-containing protein 1 (beta-amyloid-binding protein, hBBP, TM2D1, BBP)

Function: - may participate in beta-amyloid-induced apoptosis via its interaction with beta-APP42 - interacts with beta-APP42 (beta-amyloid protein 42) peptide of APP - N-glycosylated Structure: belongs to the TM2 family Compartment: membrane Expression: widely expressed

General

glycoprotein membrane protein

Properties

SIZE: entity length = 207 aa MW = 22 kD COMPARTMENT: cellular membrane MOTIF: signal sequence {1-37} N-glycosylation site {N72} N-glycosylation site {N87} N-glycosylation site {N96} transmembrane domain {119-136} transmembrane domain {154-174}

Database Correlations

UniProt Q9BX74 Pfam PF05154

References

UniProt :accession Q9BX74