tiopronin; alpha-mercaptopropionylglycine (Tiola)

Tradenames: Tiola. (alpha-mercaptopropionyl glycine) Indications: - prevention of cystine renal stones in patients with severe homozygous cystinuria with urinary cystine > 500 mg/day resistant to treatment with high fluid intake, alkali, & diet modification or have had adverse effects with penicillamine Dosage: 1) start 800 mg/day 2) average effective dose is 1000 mg/day Tabs: 100 mg

General

metabolic agent (metabolic modifier) thiol; sulhydryl compound; mercaptan

References

Kaiser Permanente Northern California Regional Drug Formulary, 1998