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tick borne infection

Classification: 1) Rickettsial diseases (tick typhus) a) rickettsial spotted fever b) ehrlichiosis c) anaplasmosis 2) borreliosis (relapsing fever), Lyme disease 3) tularemia 4) babesiosis 5) Southern tick-associated rash illness 7) Powassan virus & other tick-borne encephalitides 8) pathogenic viruses * Images [7] Epidemiology: - tripled 2004-2016 [6]; doubled 2005-2018 [7] - Lyme disease culprit in 82% of tick borne infections [6] Laboratory: - serology for rickettsial spp is often negative in the acute phase of the disease - if Ehrlichia or Anaplasma is suspected, Ehrlichia DNA & Anaplasma phagocytophilum DNA is sensitive in early phases of the disease Management: - empiric treatment with doxycycline [2]

Related

tick bite tick-related allergy

Specific

anaplasmosis babesiosis borreliosis (relapsing fever) ehrlichiosis Kyasanur forest disease (Monkey fever) Lyme disease rickettsial spotted fever; tick typhus southern tick-associated rash illness (STARI) tick-borne encephalitis virus tick-bourne relapsing fever tularemia (deer fly fever, Prahvant Valley plague, rabbit fever)

General

arthropod-borne infection

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 16, American College of Physicians, Philadelphia 2012
  2. Chapman AS, Bakken JS, Folk SM et al Diagnosis and management of tickborne rickettsial diseases: Rocky Mountain spotted fever, ehrlichioses, and anaplasmosis - United States: a practical guide for physicians and other health-care and public health professionals. MMWR Recomm Rep. 2006 Mar 31;55(RR-4):1-27. PMID: 16572105
  3. Wormser GP, Dattwyler RJ, Shapiro ED et al The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2006 Nov 1;43(9):1089-134 PMID: 17029130 corresponding NGC guideline withdrawn Feb 2016
  4. Centers for Disease Control and Prevention (CDC) Recommendations on diagnosis and management of tickborne rickettsial diseases: Rocky Mountain spotted fever, ehrlichioses, and anaplasmosis http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5504a1.htm
  5. ARUP Consult: Tickborne Diseases Testing Algorithm https://arupconsult.com/algorithm/tick-borne-testing-algorithm
  6. Brooks M Mosquito and Tick Diseases a Large and Growing Threat in US. Medscape - May 01, 2018. https://www.medscape.com/viewarticle/896012 - Rosenberg R, Lindsey NP, Fischer M, et al. Vital Signs: Trends in Reported Vectorborne Disease Cases - United States and Territories, 2004-2016, MMWR Morb Mortal Wkly Rep. ePub: 1 May 2018. https://www.cdc.gov/mmwr/volumes/67/wr/mm6717e1.htm
  7. Paules CI, Marston HD, Bloom ME, Fauci AS. Tickborne Diseases - Confronting a Growing Threat. N Engl J Med 2018; 379:701-703. Aug 23, 2018 PMID: 30044925 Free full text https://www.nejm.org/doi/full/10.1056/NEJMp1807870
  8. Centers for Disease Control & Prevention (CDC) Tickborne Disease Surveillance Data Summary https://www.cdc.gov/ticks/data-summary/index.html