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thyroid-stimulating immunoglobulin (TSI) in serum

Indications: - suspected Graves disease - suspected euthyroid Graves ophthalmopathy - pregnancy complicated by Graves disease - atypical fluctuating hypothyroidism or hyperthyroidism Clinical significance: - antibody stimulating TSH receptors in thyroid, autonomous with regard to negative feedback from T3, T4

Related

anti-thyrotropin Graves disease (Basedow's disease, exothalmic goiter) thyrotropin receptor antibody; TSH receptor antibody

General

serology

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 15, American College of Physicians, Philadelphia 2009
  2. Thyroid Stimulating Immunoglobulin Laboratory Test Directory ARUP: 99430 Laboratory Test Directory ARUP: 3002287 - TSH Receptor Antibody Laboratory Test Directory ARUP: 2002734