thyroid hormone receptor-associated protein 3; thyroid hormone receptor-associated protein complex 150 kD component; trap150 (THRAP3, TRAP150)

Function: - role in transcriptional coactivation - phosphorylated upon DNA damage, probably by ATM or ATR - subunit of the large multiprotein complex TRAP Compartment: nucleus (putative) Expression: ubiquitous

General

phosphoprotein transcription factor (TF)

Properties

SIZE: entity length = 955 aa MW = 109 kD COMPARTMENT: cell nucleus MOTIF: Ser phosphorylation site {S2} serine-rich region {7-339} MOTIF: serine residue (SEVERAL) arginine-rich region {12-161} MOTIF: arginine residue (SEVERAL) Ser phosphorylation site {S51} Ser phosphorylation site {S53} Ser phosphorylation site {S55} Ser phosphorylation site {S119} Ser phosphorylation site {S134} Ser phosphorylation site {S207} Ser phosphorylation site {S211} Ser phosphorylation site {S232} Ser phosphorylation site {S237} Ser phosphorylation site {S240} Ser phosphorylation site {S243} Ser phosphorylation site {S248} Ser phosphorylation site {S253} Ser phosphorylation site {S264} Ser phosphorylation site {S268} Ser phosphorylation site {S310} Ser phosphorylation site {S315} Ser phosphorylation site {S320} Ser phosphorylation site {S323} Thr phosphorylation site {T324} Tyr phosphorylation site {Y328} Ser phosphorylation site {S377} Ser phosphorylation site {S379} Ser phosphorylation site {S406} Ser phosphorylation site {S408} Ser phosphorylation site {S444} Ser phosphorylation site {S508} Ser phosphorylation site {S534} Ser phosphorylation site {S535} ATP-binding site NAME: ATP-binding site SITE: 552-559 Ser phosphorylation site {S562} Ser phosphorylation site {S575} Thr phosphorylation site {T662} Ser phosphorylation site {S672} Ser phosphorylation site {S682} Ser phosphorylation site {S684} Thr phosphorylation site {T685} Ser phosphorylation site {S698} Ser phosphorylation site {S823} Thr phosphorylation site {T833} Thr phosphorylation site {T874} Ser phosphorylation site {S928} Ser phosphorylation site {S939} Thr phosphorylation site {T941}

Database Correlations

OMIM 603809 UniProt Q9Y2W1 Entrez Gene 9967 Kegg hsa:9967

References

UniProt :accession Q9Y2W1