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thyroid disease

Laboratory: - serum TSH is the most sensitive indicator of thyroid function in ambulatory patients with intact pituitary function [2] - in sick elderly patients, both serum TSH & free T4 should be used to evaluate thyroid function [4] - see ARUP consult [1] Special Laboratory: - thyroid ultrasound - indications - screening - history of radiation exposure to head & neck - MEN2 - family history of thyroid carcinoma - routine screening not recommended [5] - diagnostic - unexplained cervical lymphadenopathy - evaluation of thyroid nodule - guidance for FNA of thyroid nodule(s)

Related

thyroid

Specific

developmental thyroid disease euthyroid sick syndrome; nonthyroidal illness syndrome; low T3 syndrome (ESS) goiter Graves disease (Basedow's disease, exothalmic goiter) hyperthyroidism hypothyroidism myxedema; thyroid dermopathy (includes myxedema coma) syndrome of thyroid hormone resistance; generalized thyroid hormone resistance; Refetoff syndrome thyroglossal cyst/nodule (thyrolingual cyst) thyroid C-cell hyperplasia; C-cell proliferative disorder thyroid neoplasm (nodule) thyroid nodule thyroiditis

General

endocrine disease

References

  1. ARUP Consult: Thyroid Disease The Physician's Guide to Laboratory Test Selection & Interpretation https://arupconsult.com/content/thyroid-disease - Thyroid Disorders Testing Algorithm https://arupconsult.com/algorithm/thyroid-disorders-testing-algorithm
  2. Medical Knowledge Self Assessment Program (MKSAP) 16, 18. American College of Physicians, Philadelphia 2012, 2018.
  3. Leonhardt JM, Heymann WR. Thyroid disease and the skin. Dermatol Clin. 2002 Jul;20(3):473-81, vii. PMID: 12170880
  4. Geriatric Review Syllabus, 8th edition (GRS8) Durso SC and Sullivan GN (eds) American Geriatrics Society, 2013
  5. U.S. Preventive Servies Task Force (USPSTF) Draft Recommendation Statement. Oct. 2014 Thyroid Dysfunction: Screening http://www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementDraft/thyroid-dysfunction-screening
  6. Tabatabaie V, Surks MI. The aging thyroid. Curr Opin Endocrinol Diabetes Obes. 2013 Review. PMID: 23974775
  7. Aslam R, Steward D. Surgical management of thyroid disease. Otolaryngol Clin North Am. 2010 Apr;43(2):273-83, viii. Review. PMID: 20510714
  8. Boelaert K. Thyroid dysfunction in the elderly. Nat Rev Endocrinol. 2013 Apr;9(4):194-204. Review. PMID: 23438834
  9. Alexander EK, Pearce EN, Brent GA et al 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease during Pregnancy and the Postpartum. Thyroid. Jan 6. 2017 PMID: 28056690 http://online.liebertpub.com/doi/pdfplus/10.1089/thy.2016.0457