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thymus-specific serine protease; serine protease 16 (PRSS16, TSSP)
Function:
- serine protease
- may play a role in T-cell development
Structure:
- belongs to the peptidase S28 family
Compartment:
- cytoplasmic vesicle
- vesicular, either lysosomal or endosomal
Expression:
- expressed predominantly in cortical thymic epithelial cells
- expressed in fetal thymus
General
glycoprotein
serine protease
Properties
SIZE: entity length = 514 aa
MW = 55 kD
COMPARTMENT: lysosome
cytoplasm
endosome
MOTIF: signal sequence {1-24}
N-glycosylation site {N70}
N-glycosylation site {N172}
serine residue {S185}
N-glycosylation site {N321}
aspartate residue {D447}
histidine residue {H472}
Database Correlations
OMIM 607169
UniProt Q9NQE7
Pfam PF05577
Entrez Gene 10279
Kegg hsa:10279
References
UniProt :accession Q9NQE7