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thymus high mobility group box protein TOX; thymocyte selection-associated high mobility group box protein TOX (TOX, KIAA0808)
Function:
- role in regulating T-cell development (putative)
Structure:
- contains 1 HMG box DNA-binding domain
Compartment: nucleus
General
human longevity protein
nuclear protein
Properties
SIZE: MW = 58 kD
entity length = 526 aa
COMPARTMENT: cell nucleus
MOTIF: nuclear translocation signal {237-256}
HMG box
SITE: 261-329
proline-rich region
SITE: 417-420
MOTIF: proline residue (SEVERAL)
Database Correlations
OMIM 606863
UniProt O94900
Pfam PF00505
Entrez Gene 9760
Kegg hsa:9760
References
UniProt :accession O94900