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thrombosis
The clotting of blood within a blood vessel.
Epidemiology:
1) 2,000,000 deaths/year due to thrombotic events
2) most common cause of death in US, includes
a) deep venous thrombosis (DVT)
b) pulmonary embolus (PE)
c) myocardial infarction (MI)
d) embolic stroke
3) more than 1/2 have acquired or inherited coagulation defect
Pathology:
- arterial thrombosis & venous thrombosis manifestations of underlying hypercoagulability [4]
Related
coagulation cascade
thrombotic disorder
Trousseau's syndrome; Trousseau's sign of malignancy; thrombophlebitis migrans
Specific
arterial thrombosis
arteriovenous fistula (AV) thrombosis
mechanical valve thrombosis; prosthetic valve thrombosis
pulmonary thrombosis
thromboembolism
venous thrombosis
General
sign/symptom
References
- Contributions from Linda Kuribayashi MD, Dept of
Medicine, UCSF Fresno
- Harrison's Principles of Internal Medicine, 13th ed.
Isselbacher et al (eds), McGraw-Hill Inc. NY, 1994, pg 1140
- Guyatt GH, Norris SL, Schulman S et al
Methodology for the development of antithrombotic therapy and
prevention of thrombosis guidelines: Antithrombotic Therapy
and Prevention of Thrombosis, 9th ed: American College of
Chest Physicians Evidence-Based Clinical Practice Guidelines.
Chest. 2012 Feb;141(2 Suppl):53S-70S
PMID: 22315256
- Green D
Elevated Risk for Thrombotic Events After Superficial Venous
Thrombosis
Physician's First Watch, Jan 15, 2015
David G. Fairchild, MD, MPH, Editor-in-Chief
Massachusetts Medical Society
http://www.jwatch.org