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Threonine synthase-like 2 (TSH2, THNSL2)
Function:
- acts as a catabolic phospho-lyase on both gamma- & beta-phosphorylated substrates
- degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia & phosphate
Cofactor: pyridoxal phosphate (putative)
Structure: belongs to the serine/threonine dehydratase family
Alternative splicing: named isoforms=4
General
lyase
Properties
SIZE: entity length = 484 aa
MW = 54 kD
MOTIF: cofactor-binding site [113-113]
FOR-BINDING-OF: pyridoxal phosphate
Database Correlations
UniProt Q86YJ6
Pfam PF00291
References
UniProt :accession Q86YJ6