cysteine/serine-rich nuclear protein 1; CSRNP-1; axin-1 up-regulated gene 1 protein; protein URAX1; TGF-beta-induced apoptosis protein 3; TAIP-3 (CSRNP1, AXUD1, TAIP3)

Function: - binds to the consensus sequence 5'-AGAGTG-3' - has transcriptional activator activity (putative) - may have a tumor-suppressor function - may play a role in apoptosis Structure: belongs to the AXUD1 family Compartment: nucleus (putative) Expression: - ubiquitous - most abundantly expressed in lung, placenta, skeletal muscle, pancreas & leukocytes - frequently down-regulated in lung cancer, kidney cancer, liver cancer & colon cancers

Properties

SIZE: entity length = 589 aa MW = 64 kD COMPARTMENT: cell nucleus MOTIF: serine-rich region {17-40} MOTIF: serine residue (SEVERAL) cysteine-rich region {237-275}

Database Correlations

OMIM 606458 UniProt Q96S65

References

UniProt :accession Q96S65