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tetranectin; TN; C-type lectin domain family 3 member B; plasminogen kringle 4-binding protein (CLEC3B TNA)

Function: - tetranectin binds to plasminogen & to isolated kringle 4 - may be involved in the packaging of molecules destined for exocytosis Structure: - homotrimer - contains 1 C-type lectin domain Compartment: secreted Expression: found in plasma

General

lectin secreted protein

Properties

SIZE: entity length = 202 aa MW = 23 kD COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-21} Thr glycosylation site {T25} cysteine residue {C71} MODIFICATION: cysteine residue {C81} C-type lectin {77-198} MOTIF: cysteine residue {C81} MODIFICATION: cysteine residue {C71} cysteine residue {C98} MODIFICATION: cysteine residue {C197} cysteine residue {C173} MODIFICATION: cysteine residue {C189} cysteine residue {C189} MODIFICATION: cysteine residue {C173} cysteine residue {C197} MODIFICATION: cysteine residue {C98}

Database Correlations

OMIM 187520 UniProt P05452 Pfam PF00059 Entrez Gene 7123 Kegg hsa:7123

References

  1. UniProt :accession P05452
  2. Functional glycomics gateway - glycan binding http://www.functionalglycomics.org