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testis-specific prion protein (Protein M8) (PRNT)

Compartment: secreted (putative) Expression: specifically expressed in adult testis Evolution: - this putative protein is only present in primates & not in other mammals Note: - could be the product of a pseudogene - related to the prion family because it is found in the same genomic cluster as PRNP & PRND - however, it does not share any sequence similarity with these 2 proteins

General

glycoprotein secreted protein

Properties

SIZE: entity length = 94 aa MW = 11 kD COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-18} N-glycosylation site {N44}

Database Correlations

UniProt Q86SH4 Kegg hsa:1498

References

  1. UniProt :accession Q86SH4
  2. Makrinou E, Collinge J, Antoniou M. Genomic characterization of the human prion protein (PrP) gene locus. Mamm Genome. 2002 Dec;13(12):696-703. PMID: 12514748