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teneurin-3; Ten-3; tenascin-M3; Ten-m3, protein Odd Oz/ten-m homolog 3 (TENM3, ODZ3, KIAA1455, TNM3)
Function:
1) cellular signal transducer (putative)
2) cytoplasmic proline-rich regions could serve as docking domains for intracellular SH3-containing proteins
- contains 8 EGF-like domains
- contains 5 NHL repeats
- contains 1 teneurin N-terminal domain
- contains 23 YD repeats
Structure: homodimer, disulfide-linked
Compartment: membrane
Expression:
- expressed in adult & fetal brain > testis, ovary > other peripheral tissues
- not expressed in spleen or liver
- in brain, expressed in amygdala & caudate nucleus > thalamus, subthalamicnucleus
General
oligomerizing protein
teneurin
Properties
SIZE: MW = 301 kD
entity length = 2699 aa
COMPARTMENT: plasma membrane
MOTIF: TENEURIN N-TERMINAL {10-308}
transmembrane domain {311-331}
N-glycosylation site {N345}
N-glycosylation site {N380}
N-glycosylation site {N419}
EGF domain {514-774} (8)
MOTIF: cysteine residue {C518}
MODIFICATION: cysteine residue {C528}
cysteine residue {C522}
MODIFICATION: cysteine residue {C533}
cysteine residue {C528}
MODIFICATION: cysteine residue {C518}
cysteine residue {C533}
MODIFICATION: cysteine residue {C522}
cysteine residue {C535}
MODIFICATION: cysteine residue {C544}
cysteine residue {C544}
MODIFICATION: cysteine residue {C535}
N-glycosylation site {N860}
N-glycosylation site {N883}
NHL repeat domain {1200-1501} (5)
MOTIF: N-glycosylation site {N1202}
YD {1511-2316} (23)
MOTIF: N-glycosylation site {N1527}
N-glycosylation site {N2576}
Database Correlations
UniProt Q9P273
References
UniProt :accession Q9P273