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teneurin-2; Ten-2; tenascin-M2; Ten-m2; protein Odd Oz/ten-m homolog 2 (TENM2, ODZ2, KIAA1127, TNM2)
Function:
1) cellular signal transducer (putative)
2) cytoplasmic proline-rich regions could serve as docking domains for intracellular SH3-containing proteins
3) tenascin family, teneurin subfamily
- contains 8 EGF-like domains
- contains 5 NHL repeats
- contains 23 YD repeats STructure: homodimer, disulfide-linked
Compartment: membrane
Expression:
- expressed in heart > brain, liver, kidney, fetal brain > lung, testis
- no expression in skeletal muscle, pancreas, spleen, ovary, fetal liver
General
oligomerizing protein
teneurin
Properties
SIZE: MW = 308 kD
entity length = 2774 aa
COMPARTMENT: plasma membrane
MOTIF: TENEURIN N-TERMINAL {9-374}
MOTIF: serine-rich region {175-178}
MOTIF: serine residue (SEVERAL)
serine-rich region {331-334}
MOTIF: serine residue (SEVERAL)
transmembrane domain {380-400}
N-glycosylation site {N443}
N-glycosylation site {N482}
EGF domain {575-841} (8)
MOTIF: cysteine residue {C576}
MODIFICATION: cysteine residue {C586}
cysteine residue {C580}
MODIFICATION: cysteine residue {C591}
cysteine residue {C586}
MODIFICATION: cysteine residue {C576}
cysteine residue {C591}
MODIFICATION: cysteine residue {C580}
cysteine residue {C593}
MODIFICATION: cysteine residue {C602}
N-glycosylation site {N925}
N-glycosylation site {N948}
N-glycosylation site {N1267}
NHL repeat domain {1272-1316} (5)
YD {1583-1602} (23)
N-glycosylation site {N2648}
Database Correlations
UniProt Q9NT68
References
UniProt :accession Q9NT68