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tectorin-beta (TECTB)
Function:
1) one of the major non-collagenous components of the tectorial membrane
2) may form homomeric filament after self-association or heteromeric filament after association with alpha-tectorin
Compartment:
- cell membrane, lipid-anchor, GPI-anchor
- targeted to the apical surface of the inner ear epithelia & proteolytically released into the extracellular compartment
General
tectorin
Properties
SIZE: MW = 37 kD
entity length = 329 aa
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-17}
ZP domain {19-283}
MOTIF: cysteine residue {*1}
MODIFICATION: cysteine residue {*2}
cysteine residue {*2}
MODIFICATION: cysteine residue {*1}
N-glycosylation site {N80}
N-glycosylation site {N104}
N-glycosylation site {N116}
N-glycosylation site {N145}
glycosyl phosphatidylinositol [GPI] membrane anchor {C-TERMINUS}
Database Correlations
OMIM 602653
UniProt Q96PL2
Pfam PF00100
References
- OMIM :accession 602653
- UniProt :accession Q96PL2