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TATA box-binding protein-like protein 2 (TBP-like protein 2, TATA box-binding protein-related factor 3, TBP-related factor 3, TBPL2, TRF3)
Function:
- transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes
- the complex replaces TFIID at specific promoters at an early stage in the differentiation process (putative)
- interacts with TAF3 (putative)
Structure: belongs to the TBP family
Compartment:
- cytoplasm. nucleus
- present in the cytoplasm during cytokenesis
Expression:
- ubiquitously expressed in all tissues examined
- highest levels in heart, lung, ovary, spleen & testes
General
transcription factor (TF)
Properties
SIZE: entity length = 375 aa
MW = 42 kD
COMPARTMENT: cytoplasm
cell nucleus
MOTIF: proline-rich region
SITE: 22-26
MOTIF: proline residue (SEVERAL)
Database Correlations
UniProt Q6SJ96
Pfam PF00352
Kegg hsa:3873
References
UniProt :accession Q6SJ96