TATA box-binding protein-associated factor RNA polymerase 1 subunit C (TATA box-binding protein-associated factor 1C, TBP-associated factor 1C, TBP-associated factor RNA polymerase I 110 kD, TAFI110, TAF1C)

Function: 1) component of the transcription factor SL1/TIFIB complex 2) in the complex interacts directly with TBP, TAF1A & TAF1B. 3) interacts with MYC, RRN3 & p53/TP53 with low affinity 4) recruits RNA polymerase 1 to the rRNA gene promoter via interaction with RRN3 Compartment: nucleus Alternative splicing: named isoforms=3

General

nuclear protein protein subunit

Properties

SIZE: MW = 95 kD entity length = 869 aa COMPARTMENT: cell nucleus

Database Correlations

OMIM 604905 UniProt Q15572

References

UniProt :accession Q15572