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TATA-binding protein-associated factor (TAF, TBP-associated factor)

TAFs are subunits of TFIID excluding the TATA-binding protein (TBP or p38TFIID) {allegedly 13 in humans} & transcription factors associated with TBP in complexes facilitating transcription by RNA polymerase-1 (SL1) & RNA polymerase-3 (TFIIB). SNAP43, SNAP45 & SNAP50 associate with TBP in SNAPc, an RNA polymerase-2 & RNA polymerase-3 associated complex. TAFs are components of the TFIID complex, the TFTC complex, the PCAF complex & the STAGA complex.

Specific

p95 transcription factor IID (p95TFIID) RNA polymerase 1 promoter selectivity factor SL1 small nuclear RNA-activating protein-43; SNAPc 43 kDa subunit; proximal sequence element-binding transcription factor gamma subunit; PSE-binding factor gamma subunit; PTF gamma subunit (SNAP43, SNAPC1) small nuclear RNA-activating protein-45; SNAPc 45 kDa subunit; proximal sequence element-binding transcription factor delta subunit; PSE-binding factor delta subunit; PTF delta subunit (SNAP45) small nuclear RNA-activating protein-50; SNAPc 50 kDa subunit; proximal sequence element-binding transcription factor beta subunit; PSE-binding factor beta subunit; PTF beta subunit (SNAP50, SNAPC3) TFIIIB transcription initiation factor TFIID subunit 10; STAF28; transcription initiation factor TFIID 30 kD subunit; TAF(II)30; TAFII-30; TAFII30 (TAF10, TAF2A, TAF2H, TAFII30) transcription initiation factor TFIID subunit 12; transcription initiation factor TFIID 20/15 kD subunits; TAFII-20/TAFII-15; TAFII20/TAFII15 (TAF12, TAF15, TAF2J, TAFII20) transcription initiation factor TFIID subunit 1; cell cycle gene 1 protein; TBP-associated factor 250 kD; p250; transcription initiation factor TFIID 250 kD subunit; TAF(II)250; TAFII-250; TAFII250 (TAF1, BA2R, CCG,1 CCGS, TAF2A) transcription initiation factor TFIID subunit 4; p136TFIID; RNA polymerase II TBP-associated factor subunit C; TBP-associated factor 4; transcription initiation factor TFIID 130 kD subunit; TAF(II)130; TAFII-130; TAFII130; transcription initiation factor TFIID 135 kD subunit; TAF(II)135; TAFII-135; TAFII135 (TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135) transcription initiation factor TFIID subunit 5; p100TFIID; transcription initiation factor TFIID 100 kD subunit; TAF(II)100; TAFII-100; TAFII100 (TAF5, TAF2D) transcription initiation factor TFIID subunit 6; p70TFIID; RNA polymerase II TBP-associated factor subunit E; transcription initiation factor TFIID 70 kD subunit; TAF(II)70; TAFII-70; TAFII70; transcription initiation factor TFIID 80 kD subunit; TAF(II)80; TAFII-80; TAFII80 (TAF6, TAF2E, TAFII70) transcription initiation factor TFIID subunit 7; RNA polymerase II TBP-associated factor subunit F; transcription initiation factor TFIID 55 kD subunit; TAF(II)55; TAFII-55; TAFII55 (TAF7, TAF2F, TAFII55) transcription initiation factor TFIID subunit 9; RNA polymerase II TBP-associated factor subunit G; STAF31/32; transcription initiation factor TFIID 31 kD subunit; TAFII-31; TAFII31; transcription initiation factor TFIID 32 kD subunit; TAFII-32; TAFII32 (TAF9, TAF2G, TAFII31)

General

transcription factor (TF)

References

  1. Chiang CM, Roeder RG. Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators. Science. 1995 Jan 27;267(5197):531-6. PMID: 7824954
  2. Henry RW, Sadowski CL, Kobayashi R, Hernandez N. A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III. Nature. 1995 Apr 13;374(6523):653-6. PMID: 7715707