Target of EGR1 protein 1 (TOE1)

Function: - inhibits cell growth rate & cell cycle - induces CDKN1A expression as well as TGF-beta expression - mediates inhibitory growth effect of EGR1 Structure: - belongs to the CAF1 family - contains 1 C3H1-type zinc finger Compartment: - nucleus, nucleolus, nuclear speckle - localizes to nuclear speckles

General

nuclear protein phosphoprotein zinc finger protein

Properties

SIZE: MW = 57 kD entity length = 510 aa COMPARTMENT: cell nucleus MOTIF: Ser phosphorylation site {S5} Zinc finger NAME: Zinc finger SITE: 295-321 EFFECTOR-BOUND: Zn+2 nuclear translocation signal {335-347}

Database Correlations

UniProt Q96GM8 PFAM correlations

References

UniProt :accession Q96GM8