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syntrophin (dystrophin-associated protein)
Syntrophins are found at neuromuscular & synaptic junctions.
Specific
alpha-1-syntrophin; 59 kD dystrophin-associated protein A1 acidic component 1; Pro-TGF-alpha cytoplasmic domain-interacting protein 1; TACIP1; syntrophin-1 (SNTA1 SNT1)
beta-1-syntrophin; 59 kD dystrophin-associated protein A1 basic component 1; DAPA1B; Tax interaction protein 43; TIP-43; syntrophin-2; BSYN2 (SNTB1, SNT2B1)
beta-2-syntrophin; 59 kD dystrophin-associated protein A1 basic component 2; syntrophin-3; SNT3; syntrophin-like; SNTL (SNTB2 D16S2531E SNT2B2 SNTL)
gamma-1-syntrophin; G1SYN; syntrophin-4; SYN4 (SNTG1)
gamma-2-syntrophin; G2SYN; syntrophin-5; SYN5 (SNTG2)
General
cytoskeletal protein
Properties
COMPARTMENT: cytoplasm
MOTIF: DHR domain
Database Correlations
OMIM 601017
MORBIDMAP 601017
References
- Ponting CP, Phillips C.
DHR domains in syntrophins, neuronal NO synthases and other
intracellular proteins.
Trends Biochem Sci. 1995 Mar;20(3):102-3.
PMID: 7535955
Component-of
dystrophin associated protein complex (DPC)