synleurin (LRRC70 UNQ1891/PRO4337)

Function: - renders cells highly sensitive to the activation by cytokines & lipopolysaccharide (LPS) Structure: contains 13 LRR repeats (leucine-rich repeats) Compartment: membrane (potential) Expression: - expressed at low levels in many tissues, including smooth muscle, brain, uterus, pancreas, cartilage, adipose, spleen & testis

General

glycoprotein membrane protein

Properties

SIZE: entity length = 622 aa MW = 70 kD COMPARTMENT: cellular membrane MOTIF: signal sequence {1-31} leucine-rich repeat SITE: 58-82 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 83-106 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 107-130 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 131-154 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 156-178 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 179-202 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 203-226 MOTIF: leucine residue (SEVERAL) N-glycosylation site {N215} leucine-rich repeat SITE: 228-250 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 252-274 MOTIF: leucine residue (SEVERAL) N-glycosylation site {N266} leucine-rich repeat SITE: 275-298 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 300-322 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 324-347 MOTIF: leucine residue (SEVERAL) N-glycosylation site {N331} N-glycosylation site {N400} leucine-rich repeat SITE: 488-509 MOTIF: leucine residue (SEVERAL) transmembrane domain {527-547}

Database Correlations

UniProt Q7Z2Q7 PFAM correlations

References

UniProt :accession Q7Z2Q7