synaptoporin (SYNPR)

Function: 1) intrinsic membrane protein of small synaptic vesicles 2) vesicular channel protein (putative) Structure: 1) belongs to the synaptophysin/synaptobrevin family. 2) contains 1 MARVEL domain Compartment: - cytoplasmic vesicle, secretory vesicle, synaptic vesicle - synaptic vesicle membrane

General

glycoprotein ion channel transmembrane 4 protein

Properties

SIZE: MW = 29 kD entity length = 265 aa COMPARTMENT: synaptic vesicle CELL-REGION: axon terminal CELL: neuron WITHIN: brain MOTIF: cytoplasmic domain {1-4} transmembrane domain {5-25} Vesicular (Potential) {26-81} exoplasmic loop {26-81} MOTIF: N-glycosylation site {N33} N-glycosylation site {N38} transmembrane domain {82-102} cytoplasmic loop {103-114} transmembrane domain {115-135} exoplasmic loop {136-177} transmembrane domain {178-198} cytoplasmic domain {199-265} MOTIF: consensus repeat {210-214} consensus repeat {222-226} consensus repeat {227-231} consensus repeat {232-236} consensus repeat {238-242}

Database Correlations

UniProt Q8TBG9 Pfam PF01284 Entrez Gene 132204 Kegg hsa:132204

References

UniProt :accession Q8TBG9