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synaptonemal complex protein 2 (SCP-2, synaptonemal complex lateral element protein, hsSCP2, SYCP2, SCP2)
Function:
1) component of axial/lateral elements of synaptonemal complexes during meiotic prophase
2) role in organization of chromatin by temporarily binding to DNA scaffold attachment regions
3) requires SYCP3, but not SYCP1, to be incorporated into axial/lateral elements
4) heterodimer with SYCP3
5) interacts with SYCP3, SMC1L1 & SMC3
Compartment:
- nucleus
- in axial/lateral elements of tripartite segments of synaptonemal complexes
General
nuclear protein
Properties
SIZE: MW = 176 kD
entity length = 1530 aa
COMPARTMENT: cell nucleus
MOTIF: serine-rich region {655-660}
MOTIF: serine residue (SEVERAL)
Database Correlations
OMIM 604105
UniProt Q9BX26
References
UniProt :accession Q9BX26