SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2; 60 kD BRG-1/Brm-associated factor subunit B; BRG1-associated factor 60B; BAF60B (SMARCD2, BAF60B, PRO2451)

Function: - role in transcriptional activation & repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) - component of the BAF complex Structure: - belongs to the SMARCD family - contains 1 SWIB domain Compartment: nucleus Alternative splicing: named isoforms=2 Expression: - expressed in liver, lung, muscle, pancreas & placenta

General

BRG1 associated factor nuclear protein phosphoprotein SWI/SNF-related matrix-associated actin dependent regulator of chromatin subfamily D

Properties

SIZE: entity length = 456 aa MW = 52 kD COMPARTMENT: cell nucleus MOTIF: Thr phosphorylation site {T142} SWIB {232-307} Thr phosphorylation site {T408}

Database Correlations

OMIM 601736 UniProt Q92925 Pfam PF02201

References

UniProt :accession Q92925