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surfeit locus protein 6 (SURF6, SURF-6)
Function:
- binds to both DNA & RNA in vitro, with a stronger binding capacity for RNA
- may represent a nucleolar constitutive protein involved in ribosomal biosynthesis or assembly
Structure: belongs to the SURF6 family
Compartment:
- nucleus, nucleoplasm, nucleolus
- granular component of the nucleolus (putative)
General
nuclear protein
phosphoprotein
Properties
SIZE: entity length = 361 aa
MW = 41 kD
COMPARTMENT: cell nucleus
MOTIF: nuclear translocation signal {45-49}
Ser phosphorylation site {S74}
Ser phosphorylation site {S138}
nuclear translocation signal {154-158}
Ser phosphorylation site {S206}
Thr phosphorylation site {T229}
Database Correlations
OMIM 185642
UniProt O75683
Pfam PF04935
Entrez Gene 6838
Kegg hsa:6838
References
UniProt :accession O75683