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surfeit locus protein 5; mediator of RNA polymerase II transcription subunit 22; mediator complex subunit 22; Surf-5 (MED22, SURF5)
Function:
- component of the mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase 2-dependent genes
Structure: belongs to the mediator complex subunit 22 family
Compartment: nucleus (probable)
Alternative splicing: named isoforms=2; Surf5B, Surf5A
Related
surfeit-5 [SURF5] gene
General
nuclear protein
Properties
SIZE: entity length = 200 aa
MW = 22 kD
COMPARTMENT: cell nucleus
MOTIF: coiled coil {93-122}
serine-rich region {136-140}
MOTIF: serine residue (SEVERAL)
Database Correlations
OMIM 185641
UniProt Q15528
Entrez Gene 6837
Kegg hsa:6837
References
UniProt :accession Q15528
Component-of
mediator complex (mediator of RNA polymerase 2 transcription)