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suppressor of tumorigenicity protein 7 (protein HELG) (ST7 FAM4A1 HELG RAY1)
Function: may act as a tumor suppressor
Structure: belongs to the ST7 family
Compartment: membrane (putative)
Alternative splicing: named isoforms=7
Expression: ubiquitously expressed, with highest levels in heart, liver & pancreas
Related
low density lipoprotein (LDL) receptor related protein (LRP) 12 (suppressor of tumorigenicity protein 7, ST7)
suppressor of tumorigenicity protein 7-like protein (ST7-related protein) (ST7L ST7R)
General
anti-oncoprotein (tumor suppressor protein)
glycoprotein
membrane protein
Properties
SIZE: entity length = 585 aa
MW = 67 kD
COMPARTMENT: cellular membrane
MOTIF: transmembrane domain {15-35}
N-glycosylation site {N47}
transmembrane domain {62-82}
transmembrane domain {512-532}
Database Correlations
OMIM 600833
UniProt Q9NRC1
Pfam PF04184
References
UniProt :accession Q9NRC1